Mr. Ming-Hin Chau
Various naturally existing supramolecular assemblies and polymers in aqueous media have been identified and served as a source of inspiration for designing synthetic supramolecular assembled systems.1 Visible-light driven photoresponsive molecular systems could be advantageous in terms of improved biocompatibility. Red-light responsive N-alkyl and N-aryl indigos have been demonstrated with improved thermal half-life.2 To exert the full potential of photoswitchability and supramolecular assembly of indigo switch, herein, we report the design and synthesize of N,N’-alkyl-aryl-substituted indigo amphiphiles(IA). The molecular IA is composed of a hydrophilic part of a charged end-group connected with an alkyl-linker to the mono-N-aryl-substituted indigo core. Through investigation of the photoisomerisation and supramolecular transformation processes, this approach could open up new strategies towards the development of red-light controlled biomedical soft functional materials.
- S. Chen, R. Costil, F. K. C. Leung and B. L. Feringa, Angew. Chem., Int. Ed. 2021, 60, 11604–11627.
- C. Y. Huang, A. Bonasera, L. Hristov, Y. Garmshausen, B. M. Schmidt, D. Jacquemin and S. Hecht, J. Am. Chem. Soc, 2017, 139, 15205–15211.